Biomedical sciences publications Archives - SRI https://www.sri.com/category/publication/biosciences-health-pubs/ A global leader in R&D with deep roots in Silicon Valley. Fri, 05 Jan 2024 20:24:25 +0000 en-US hourly 1 https://wordpress.org/?v=6.6.2 https://www.sri.com/wp-content/uploads/2023/10/cropped-future-cube-bg-white-32x32.png Biomedical sciences publications Archives - SRI https://www.sri.com/category/publication/biosciences-health-pubs/ 32 32 Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy https://www.sri.com/publication/biosciences-health-pubs/human-sleep-program-pubs/deficiency-of-orexin-signaling-during-sleep-is-involved-in-abnormal-rem-sleep-architecture-in-narcolepsy/ Thu, 05 Oct 2023 17:36:00 +0000 https://www.sri.com/?p=81096 SRI - A global leader in R&D with deep roots in Silicon Valley.

Here, we determined the activity dynamics of orexin neurons during sleep that suppress the abnormal REM sleep architecture of narcolepsy.

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Identification and characterization of screen use trajectories from late childhood to adolescence in a US-population based cohort study https://www.sri.com/publication/biosciences-health-pubs/human-sleep-program-pubs/identification-and-characterization-of-screen-use-trajectories-from-late-childhood-to-adolescence-in-a-us-population-based-cohort-study/ Fri, 22 Sep 2023 17:35:00 +0000 https://www.sri.com/?p=81094 SRI - A global leader in R&D with deep roots in Silicon Valley.

This study will identify and characterize the subgroups of adolescents sharing similar trajectories of screen use from childhood to adolescence.

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Biological sex influences sleep phenotype in mice experiencing spontaneous opioid withdrawal https://www.sri.com/publication/biosciences-health-pubs/biological-sex-influences-sleep-phenotype-in-mice-experiencing-spontaneous-opioid-withdrawal/ Wed, 20 Sep 2023 17:33:00 +0000 https://www.sri.com/?p=81090 SRI - A global leader in R&D with deep roots in Silicon Valley.

We describe here a model of opioid withdrawal in mice that resembles the sleep phenotype characteristic of withdrawal in humans.

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Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone https://www.sri.com/publication/biosciences-health-pubs/novel-progestogenic-androgens-for-male-contraception-design-synthesis-and-activity-of-c7-%ce%b1-substituted-testosterone/ Tue, 05 Sep 2023 17:35:00 +0000 https://www.sri.com/?p=81092 SRI - A global leader in R&D with deep roots in Silicon Valley.

Male contraceptive development has included use of testosterone (T) with or without a progestin or the use of a single molecule such as progestogenic androgens (PA) for suppression of testicular T production.

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Associations between alcohol use and sex-specific maturation of subcortical gray matter morphometry from adolescence to adulthood: Replication across two longitudinal samples https://www.sri.com/publication/biosciences-health-pubs/human-sleep-program-pubs/associations-between-alcohol-use-and-sex-specific-maturation-of-subcortical-gray-matter-morphometry-from-adolescence-to-adulthood-replication-across-two-longitudinal-samples/ Sun, 03 Sep 2023 17:32:00 +0000 https://www.sri.com/?p=81086 SRI - A global leader in R&D with deep roots in Silicon Valley.

This project used generalized additive mixed models to examine sex-specific development of subcortical volumes and associations with recent alcohol use...

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Higher blood pressure and weight observed among early adolescents during the COVID-19 pandemic https://www.sri.com/publication/biosciences-health-pubs/human-sleep-program-pubs/higher-blood-pressure-and-weight-observed-among-early-adolescents-during-the-covid-19-pandemic/ Sat, 15 Jul 2023 17:27:00 +0000 https://www.sri.com/?p=81083 SRI - A global leader in R&D with deep roots in Silicon Valley.

The aim of this study is to quantify differences in blood pressure and weight before and during the COVID-19 pandemic among a demographically diverse national sample of early adolescents.

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The Menstrual Cycle and Sleep https://www.sri.com/publication/biosciences-health-pubs/human-sleep-program-pubs/the-menstrual-cycle-and-sleep/ Sat, 15 Jul 2023 16:40:00 +0000 https://www.sri.com/?p=81069 SRI - A global leader in R&D with deep roots in Silicon Valley.

Although objective sleep continuity
remains unchanged across the regular, asymptomatic menstrual cycle, activity in the sleep electroencephalogram varies.

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